Gene description for UBC
Gene name ubiquitin C
Gene symbol UBC
Other names/aliases HMG20
Species Homo sapiens
 Experiment description of studies that identified UBC in Melanoma cells

1
Experiment ID453
Identified moleculeprotein
Extracellular vesicle typeExosomes
MISEVEVs
Identification method Mass spectrometry
PubMed ID 22635005   
OrganismHomo sapiens
Experiment descriptionMelanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
AuthorsPeinado H, Alecković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D.
Journal name Nat Med
Publication year2012
SampleMelanoma cells
Sample nameB16-F10, SK-MEL-202, SK-MEL035, SK-MEL-265
Isolation/purification methods-
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK EV120019: EV-METRIC:44%, 44%, 44%

2
Experiment ID986
Identified moleculeprotein
Extracellular vesicle typeExosomes/Microvesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 25261472   
OrganismHomo sapiens
Experiment descriptionComplex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment.
AuthorsLiang Y, Eng WS, Colquhoun DR, Dinglasan RR, Graham DR, Mahal LK.
Journal name J Biol Chem.
Publication year2014
SampleMelanoma cells
Sample nameSK-MEL-5
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK EV140188: EV-METRIC:22%

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